Levomepromazine (Nozinan)


Levomepromazine is a traditional antipsychotic that is now hardly ever prescribed for schizophrenia and psychosis. It is occasionally also used to help treat severe insomnia, mania, nausea, vomiting and severe pain.


Condition for which this medication is usually prescribed

Schizophrenia

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Short description of this condition

Levomepromazine is a traditional antipsychotic that is now hardly ever prescribed for schizophrenia and psychosis. It is occasionally also used to help treat severe insomnia, mania, nausea, vomiting and severe pain.

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Effect of this medication

It slows down the effects of different substances which naturally occur in the brain, such as serotonin and dopamine. This is why it is used to treat a variety of disorders but can also have different side effects.

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Advice on this condition

Do not just stop taking this medicine. When stopping the course too early or reducing the use of this drug too quickly, withdrawal symptoms may occur. It is less effective if it is taken as the same time as antacids, like Rennies.

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Common side effects

Drowsiness/fatigue, dizziness, dry mouth and eyes, unusual or uncontrollable movements, weight gain.

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Advice with regard to these side effects

In general, your feelings of drowsiness and fatigue will diminish as you get used to the medicine. If you do suffer from drowsiness or fatigue, you can take the medicine before going to bed, but you must take care when driving. Dizziness mostly occurs when standing up too quickly. It may help to get up more slowly than usual from a sitting position. Chewing gum helps with a dry mouth because it stimulates saliva production and with dry eyes, eye drops can be used. If unusual or uncontrollable movements, such as muscle contractions, last for longer than a few days, discuss this with your doctor.


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