25 mg a day to get my too-high heart rate down ( as a result of IST disease). Very effective, even on the lowest dose my heart rate went down from 120 to 80. When I started there were a few side effects (dry mouth, pressure on my chest, fatigue), but after a few weeks they all disappeared. I started off taking them in the morning, but later I switched to taking them in the evening and I feel better for it. I'd recommend these.
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